Field of Research: Diabetes
Name of author) (s): Akram T. Kharroubi, Hisham M. Darwish, Mutaz A. Akkawi, Abdelkareem A. Ashareef, Zaher A. Almasri, Khaldoun A. Bader, and Umaiyeh M. Khammash
Title of published work: “Total Antioxidant Status in Type 2 Diabetic Patients in Palestine”
Name of Journal: Journal of Diabetes Research
Year: 2015
Volume: (2015)
Pages: 1-7
Publisher: Hindawi Publishing Corporation
Abstract:
The objective of this study was to compare the level of total antioxidant status (TAS) in type 2 diabetic and normal Palestinian subjects as well as the major factors influencing TAS levels. A sample of convenience composed of 212 type 2 diabetic and 208 normal subjects above the age of 40 were recruited. Only 9.8% of the subjects had normal body mass index (BMI) levels (<25), 29% were overweight (≥25 to <30), and 61.2% were obese (≥30). The mean levels of TAS were significantly higher in diabetic compared to control subjects (2.18 versus 1.84 mM Trolox, P = 0.001) and in hypertensive subjects compared to subjects with normal blood pressure (BP). Mean TAS levels were higher in obese compared to nonobese subjects (2.12 versus 1.85 mM Trolox, P = 0.001). Mean TAS levels were similarly higher in subjects with high fasting plasma glucose (FPG) compared to normal FPG (2.19 versus 1.90 mM Trolox) and high HbA1c (≥6.5%) compared to HbA1c < 6.5% (2.14 versus 1.91 mM Trolox). Multivariate analysis revealed that only diabetic status (P = 0.032) and the level of education (P = 0.036) were significantly associated with TAS. In conclusion diabetic patients had 18.5% increase in TAS levels compared to control subjects.
Contact author (s):
Name: Akram Kharroubi, PhD.
Address: Department of Medical Laboratory Sciences, Faculty of Health Professions
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
