Field of Research: MRI
Name of author(s): Arie Meir, Mohammad Hjouj, Liel Rubinsky and Boris Rubinsky.
Title of published work: “Magnetic Resonance Imaging of Electrolysis”
Name of Journal: Scientific Reports, Nature Publishing Group
Year: 2015
Volume: 10
Pages: 1038
Publisher’s name and address: Nature Publishing Group
Abstract:
This study explores the hypothesis that Magnetic Resonance Imaging (MRI) can image the process of electrolysis by detecting pH fronts. The study has relevance to real time control of cell ablation with electrolysis. To investigate the hypothesis we compare the following MR imaging sequences: T1 weighted,T2 weighted and Proton Density (PD), with optical images acquired using pH-sensitive dyes embedded in a physiological saline agar solution phantom treated with electrolysis and discrete measurements with a pH microprobe. We further demonstrate the biological relevance of our work using a bacterial E. Coli model, grown on the phantom. The results demonstrate the ability of MRI to image electrolysis produced pH changes in a physiological saline phantom and show that these changes correlate with cell death in the E. Coli model grown on the phantom. The results are promising and invite further experimental research.
Contact info of the contact author (s):
Name: Mohammad Hjouj, PhD.
Address: department of Medical Imaging Department / Faculty of Health Professions / Al Quds University / Jerusalem
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
